In human samples, mitochondrial superoxide dismutase 2 associates with PCa risk and Gleason score, suggesting LPA signaling may affect tumor progression through redox balance regulation (74)
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Accordingly, production of the endogenous antioxidant glutathione (GSH) by glial cells within the brain [8], particularly astrocytes [8,9,10], is a critical function, as most antioxidants are unable to cross the blood brain barrier
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